Associate/Research Scientist - Upstream Process Sciences

Key Responsibilities

• Design and execute upstream process development studies.
• Develop and optimise mammalian/CHO cell culture processes.
• Operate shake flasks, Ambr® systems and laboratory-scale bioreactors.
• Apply DoE and QbD approaches to process optimisation and characterisation.
• Support scale-up, troubleshooting, technology transfer and manufacturing activities.
• Analyse experimental data and communicate findings through reports and presentations.
• Collaborate with Cell Line Development, Analytical Sciences, Downstream Development and Manufacturing teams.
• Maintain high standards of GMP, data integrity, HSE and laboratory compliance.

About You

Essential:

• BSc or MSc in Biotechnology, Biochemical Engineering, Chemical Engineering, Molecular Biology, Cell Biology, Bioprocess Engineering or a related discipline
• Hands-on experience with mammalian/CHO cell culture and biologics process development
• Experience with Ambr® and/or laboratory-scale bioreactors
• Understanding of cell culture scale-up and process characterisation
• Experience with DoE and statistical data analysis
• Strong scientific problem-solving and troubleshooting skills

Desirable:

• Perfusion or ATF experience
• Technology transfer or manufacturing support experience
• Exposure to downstream processing or integrated process development

This role is offered on an initial 12 month contract with realistic potential for extension.

Why Apply?

An excellent opportunity to develop your career within upstream bioprocess development, gaining hands-on experience across cell culture, bioreactor systems, process optimisation, scale-up and technology transfer within a successful pharmaceutical environment.

Keywords: Upstream Process Development | Bioprocessing | Mammalian Cell Culture | CHO | Bioreactors | Ambr | Process Characterisation | Scale-Up | DoE | QbD | Perfusion | ATF | Biologics | Therapeutic Proteins | GMP | Pharmaceutical | Biopharmaceutical