About this job

An excellent opportunity for a Research Scientist to contribute to early drug discovery in the fields of Biotransformation & Enzymology!

You will be responsible for providing analytical support across a broad range of NCEs from early stage, Hit-ID to pre/ post clinical evaluation. Your primary role will be to generate LC-HRMS data from the analysis on in vivo/ in vitro samples contributing to metabolic profiling activities. You will be tasked with understanding the metabolic fate of NCEs and providing feedback to medicinal chemists regarding drug design iterations.

Essential requirements:

• Minimum PhD graduate OR BSc/ MSc in Chemistry/ Biochemistry with 3+ years industry experience in a drug discovery setting.
• Extensive knowledge & experience in HPLC, uPLC, LC- HRMS
• Experience in general in vitro lab skills
• An excellent understanding of metabolism, DMPK, ADME
• Familiarity with Thermofisher LCMS suite of equipment would be advantageous

Apply to VRS to be considered for this excellent opportunity in a leading pharmaceutical organisation!

Please note this is an initial 12 month contract.

Key words: Pharmaceutical, biopharmaceutical, Biotransformation, Enzymology, Metabolism, Metabolic profiles, NCEs, New Chemical Entities, LC-MS, LC-HRMS, HPLC, UPLC, Drug Discovery, in vitro, in vivo, Thermofisher, Waters, Agilent, Oxfordshire, Berkshire, London, Oxford, Reading, Slough, VRS8194SE

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