Analytical Chemistry, Life Science & Engineering Recruitment

Senior Research Scientist - Biotransformation


  • South East
  • £Excellent
  • Life Science

About this job

Excellent opportunity for a Biotransformation &/or Metabolite ID Specialist to join a leading pharmaceutical organization!

Working as part of a small team of Mass Spectrometry experts you will contribute to the discovery and development of novel drug candidates in the areas of Immunology & Neuroscience. You will call upon your metabolic chemistry expertise to successfully generate, report and communicate the metabolic profiles of drug candidates across a broad range of complex matrices with specific emphasis on active and reactive metabolites.


  • PhD (or equivalent) experience in Analytical Chemistry or Organic Chemistry
  • Expertise in Metabolic Chemistry with the ability to translate an in-depth knowledge of drug metabolism & physicochemical properties into the design of NCEs
  • Excellent scientific communication skills – must be able to defend work & collaborate with other departments e.g., Medicinal Chemists
  • Excellent understanding of the expression / functionality of drug metabolizing enzymes
  • Extensive experience with High Resolution Mass Spectrometry Systems - with Thermofisher systems ideally
  • Strong understanding of MIST guidelines
  • Experience working with radiolabeled drugs would be advantageous

My client are also able to accommodate a Medicinal Chemist with excellent understanding chemical structure seeking a move into the Biotransformation/ Analytical space

Apply to VRS today to be considered for this highly rewarding opportunity or contact Craig for further details!

Key Words: Biotransformation, Met ID, Metabolites, DMPK, ADME, Drug Design, NCEs, Enzymology, Radiolabeled Drugs, MIST, Mass Spectrometry, High Resolution, Thermofisher, Waters,Sciex, Agilent, Orbitrap, Q Exactive, Velos, Pharmaceuticals, United Kingdom, Berkshire, Oxfordshire, London, Oxford, Reading, Slough, VRS6897CR

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