Analytical Chemistry, Life Science & Engineering Recruitment

Senior Scientist - Upstream Process


  • North West
  • £40,000 - £50,000
  • Life Science

About this job

Excellent opportunity for a Plasmid Production Expert to make significant contribution to the Upstream Process Sciences team of a leading biopharmaceutical organisation.


  • Act as subject matter expert, to develop upstream processes for plasmid DNA production to support gene therapy programs using benchtop & pilot scale bioreactors
  • Continue to develop efficient microbial fermentation, identify scale up challenges & develop robust processes for tech transfer and manufacture
  • Manage priorities to hit key project milestones, collaborating across all of Process Sciences and wider teams

Candidate Requirements

  • PhD (or MSc) in Biochemical Engineering, Biochemistry or related
  • Extensive experience in plasmid DNA production using 250ml to 200L bioreactors – familiarity with Ambr systems is desirable
  • Thorough knowledge in analytical & molecular biology methods relevant to plasmid DNA

+ at least 3 years industry experience

Apply to VRS today!

Key Words: Process Sciences, Process Development, Upstream, Downstream, Analytical, Scale-up, Manufacture, Tech-transfer, Production, Bioreactors, 250ml, 50L, 100L, 200L, Ambr Systems, DNA, RNA, Plasmid, Gene Therapy Microbial Fermentation, Cell Culture,Molecular Biology, Biochemical Engineering, Biochemistry, PhD, South East, Berkshire, Reading, Oxford, Slough, London, VRS6664CR

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